Table 1.
Demographic and Clinical Characteristics
| Healthy Controls (n=84) | Anxiety Diagnosis (n=149) | t/χ2 | |
|---|---|---|---|
| Demographics | |||
| Age | 16.94 (5.08) | 18.38 (6.36) | 1.78 |
| Gender (% female) | 58.3% | 64.4% | 0.85 |
| Race (% Caucasian) | 48.8% | 58.4% | 1.99 |
| Study Site (% UIC) | 70.2% | 71.8% | 0.07 |
| Cortical Thickness (mm) | |||
| Right vmPFC | 2.73 (0.17) | 2.72 (0.16) | 0.57 |
| Left vmPFC | 2.61 (0.17) | 2.65 (0.16) | 1.64 |
| Right rACC | 3.08 (0.24) | 3.09 (0.22) | 0.40 |
| Left rACC | 3.01 (0.28) | 3.00 (0.23) | 0.54 |
| Right Insula | 2.99 (0.18) | 3.00 (0.16) | 0.30 |
| Left Insula | 2.99 (0.19) | 3.01 (0.18) | 0.35 |
| Clinical Characteristics | |||
| Anxiety Symptoms (z score) | −1.19 (0.26) | 0.63 (0.59) | 25.52*** |
| Generalized Anxiety Disorder | - | 73.2% | - |
| Social Anxiety Disorder | - | 61.1% | - |
| Panic Disorder | - | 18.1% | - |
| Specific Phobia | - | 18.1% | - |
| Separation Anxiety Disorder | - | 8.1% | - |
| Posttraumatic Stress Disorder | - | 8.7% | - |
| Agoraphobia | - | 4.0% | - |
| Two or More Anxiety Diagnoses | - | 59.1% | - |
| Number of Anxiety Diagnoses | - | 1.91 (0.95) | - |
Note. vmPFC=ventromedial prefrontal cortex. rACC=rostral anterior cingulate cortex.
***
p<.001.