TABLE 2.
Meta-analysis of experimental phage-bacteria infection networks and estimation of phage cocktail size.
| References | Bacteria | Phages | Fill | Temp.a | Nestedb | Φc | ||
| Hong et al. (2013) | Laboratory | 7 | Sewage | 3 | 71.4 | 0 | + | 1 |
| Shende et al. (2017) | Sewage water | 8 | Manure | 5 | 55 | 1.1 | + | 1 |
| Liao et al. (2019) | Laboratory | 17 | Non-fecal compost | 4 | 42.6 | 21.5 | + | 3 |
| Krasowska et al. (2015) | Laboratory, soil | 19 | Soil | 4 | 68.4 | 6.2 | + | 1 |
| Hwang et al. (2009) | Poultry, laboratory | 16 | Poultry, sewage, soil | 6 | 31.3 | 11.4 | + | 2 |
| Kwiatek et al. (2015) | Clinical | 20 | Sewage | 5 | 52 | 27.8 | + | 3 |
| Hammerl et al. (2016) | Laboratory | 36 | Prophage induction | 3 | 64.8 | 47.1 | − | 4 |
| Xie et al. (2016) | Laboratory | 12 | Manure, cattle feed, water, soil | 10 | 51.7 | 17.7 | + | 2 |
| Magare et al. (2017) | Air | 5 | Air | 25 | 15.2 | 31 | − | 3 |
| Álvarez et al. (2019) | Potato, laboratory | 42 | River water | 3 | 90.4 | 0 | + | 1 |
| Pereira et al. (2016) | Food, water, laboratory | 42 | Sewage | 3 | 62.7 | 0 | + | 1 |
| Yu et al. (2016) | Kiwifruit | 31 | Soil | 5 | 25.7 | 18.3 | + | 4 |
| Dias et al. (2013) | Livestock | 20 | Sewage | 10 | 92 | 10.3 | − | 2 |
| Alič et al. (2017) | Orchid, wastewater | 55 | Orchid, wastewater | 4 | 25 | 7.5 | + | 4 |
| This work (Figure 3C) | Dairy, laboratory | 26 | Manure, sewage, laboratory | 10 | 33.4 | 21.8 | + | 4 |
| Salifu et al. (2013) | Equine | 27 | Soil | 10 | 57.4 | 15.7 | + | 3 |
| Arachchi et al. (2013) | Seafood | 50 | Laboratory | 6 | 84.7 | 1 | + | 1 |
| Oh et al. (2017) | Laboratory | 27 | Fermented food, soil | 12 | 44.4 | 22.3 | + | 3 |
| Wandro et al. (2019) | Human feces | 15 | Sewage | 22 | 72.4 | 5.8 | + | 1 |
| Gunathilaka et al. (2017) | Laboratory | 12 | Sewage | 29 | 49.4 | 10.2 | + | 2 |
| Jurczak-Kurek et al. (2016) | Clinical | 60 | Sewage | 6 | 32.8 | 6 | + | 3 |
| Litt and Jaroni (2017) | Clinical, cattle feces | 54 | Cattle | 7 | 89.7 | 0 | + | 1 |
| Romero-Suarez et al. (2012) | Walnut | 16 | Walnut | 26 | 71.6 | 12.6 | + | 2 |
| Wang et al. (2015) | Cattle, human | 41 | Cattle feces | 11 | 20.2 | 23.8 | + | 5 |
| Murphy et al. (2013) | Dairy | 20 | Dairy | 24 | 31.5 | 37.3 | + | 4 |
| Sajben-Nagy et al. (2012) | Laboratory, mushroom | 34 | Mushroom | 16 | 39.3 | 12.8 | + | 3 |
| This work (Figure 3B) | Dairy | 44 | Livestock feces | 26 | 30.2 | 15.2 | + | 4 |
| Vu et al. (2019) | Vegetable, seafood, livestock | 31 | Prophage | 39 | 21.6 | 11.6 | + | 4 |
| This work (Figure 3A) | Dairy, laboratory | 56 | Fecal | 26 | 45.6 | 17.4 | + | 4 |
| Petsong et al. (2019) | Livestock | 47 | Livestock | 36 | 14.3 | 10.2 | + | 5 |
| Jäckel et al. (2017) | Laboratory | 113 | Prophage | 19 | 6.2 | 11.6 | + | 7 |
| Brady et al. (2017) | Beehive | 40 | Beehive | 57 | 40.7 | 7.7 | + | 3 |
| Gencay et al. (2019) | Pork meat | 72 | Prophage | 41 | 22.1 | 13.7 | + | 5 |
| Korf et al. (2019) | Clinical, poultry | 64 | Poultry, sewage | 50 | 18.7 | 18.2 | + | 6 |
| Mathieu et al. (2020) | Feces | 75 | Feces | 166 | 6.1 | 2.8 | + | 5 |
aTemperature measured by BMN.
bNested (+) implies p < 0.05.
cPhage cocktail size estimated by Φ2 (Figure 5B).