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. 2021 Mar 1;12(3):226. doi: 10.1038/s41419-021-03481-6

Fig. 3. CMS induces HDFs proliferation and motility by activating Piezo1.

Fig. 3

A HDFs proliferative capacity was determined by Ki67 immunofluorescent staining in the context of GsMTx4 application. (Scale bar: 100 μm). B Quantitative analysis of the percentage of Ki67 positive cells. C HDFs proliferative capacity was determined by Ki67 immunofluorescent staining in the context of Piezo1 knockdown. (Scale bar: 100 μm). D Quantitative analysis of the percentage of Ki67 positive cells. E HDFs motility was detected by the Transwell migration assay in the context of GsMTx4 application. (Scale bar: 100 μm). F Quantitative analysis of the percentage of cell migration. G HDFs motility was detected by the Transwell migration assay in the context of Piezo1 knockdown. (Scale bar: 100 μm). H Quantitative analysis of the percentage of cell migration. Results are expressed as the means with SD (n = 3). One-way ANOVA is used for all analysis. *P < 0.05, **P < 0.01, ***P < 0.005.