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. 2021 Mar 1;12:1358. doi: 10.1038/s41467-021-21587-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Reed-Solomon inner-outer encoding scheme. B Relationship between log decoder error probability during RS decoding and DNA strand length, including the effects of symbol error rate (mutations, insertions, and deletion, P_error) and copy number. C Relationship between information density of a DNA storage system and the probability of symbol erasure (strand loss due to breakage) as a function of strand length. D Relationship between information density and strand length as a function of the probability of strand breakage. C and D assume a copy number of 1.