Fig. 4.

Puerarin regulates the expression of metabolic genes in cardiac hypertrophy induced by OVX plus AAC surgery. a Reverse transcription-polymerase chain reaction analysis for carnitine palmitoyltransferase 1A (Cpt1a), carnitine palmitoyltransferase 1B (Cpt1b), long-chain acyl-CoA dehydrogenase (Lcad), and medium-chain acyl-CoA dehydrogenase (Mcad) in hearts obtained from the indicated groups. b Reverse transcription-polymerase chain reaction analysis of hexokinase 2 (Hk2), pyruvate dehydrogenase E1 component subunit alpha (Pdha1), and phosphofructokinase 1 (Pfk1) in hearts. OVX ovariectomy, AAC abdominal aortic constriction group; OVX + AAC + Pue, puerarin injected-OVX + AAC group; OVX + AAC + E2, E2 injected-OVX + AAC group; OVX + AAC + Fen, fenofibrate injected-OVX + AAC group. Data are presented as the mean ± SD. Statistical significance was determined using one-way ANOVA coupled with Tukey’s multiple comparison post hoc test. ^*P < 0.05 vs. sham group; ^#P < 0.05 vs. OVX + AAC group; data are representative of three independent experiments