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Development of a vicious cycle induced by a stressful lifestyle. Stressors promote the behavior of hypercaloric food binge which, in turn, increases the release of catecholamines and cortisol (immunosuppressants). Subsequently, catecholamines induce glycolysis, reinforce the maladaptive eating patterns, and negatively modulate immune cell activity. On the other hand, cortisol induces chronic immunosuppression.
