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. 2021 Feb 16;8:622225. doi: 10.3389/fmed.2021.622225

Table 2.

Estimated cumulative glucocorticoid doses in a 24-week period for a 60 kg patient in different induction to remission schemes.

Regimen Methylprednisolone total cumulative dose (g) Oral prednisone total cumulative dose (g) Oral prednisone average dose (mg/day) Total GC dose (g)
Modified NIH, 2001 (76) 9.00 2.84 16.9 11.8
ELNT, 2002 (77) 2.25 3.12 18.5 5.37
ALMS, 2009 (85) 4.27 25.4 4.27
MYLUPUS, 2011 (80) 1.50 2.14 12.7 3.64
RITUXILUP, 2013 (86) 1.00 1.00
LupusCRUCES, 2014 (48) 1.50-3.00 1.30-1.50 8.0-9.0 2.80–4.50
Chinese multitarget, 2015 (81) 1.5 3.25 16.2 4.75
4+2 Rituximab, 2015 (87) 2.70 2.52 15.0 5.22
AURA-LV, 2019 (84) 1.00 1.33 7.9 2.33
BLISS-LN, 2020 (88) 0.50–3.00* 3.12–4.27 18.5–25.4 3.12–4.27
NOBILITY, 2020 (89) 0.75–3.00* 1.79–1.93 10.6–11.5 1.79–1.93
*

Methylprednisolone pulses elective at discretion of the investigator.