TABLE 2.

Differences in ALFF under slow-4 and slow-5 bands among CN, SCD, naMCI, and aMCI.

Brain regions (aal)		Peak MNI coordinate			F/T-values	Cluster size (mm3)
		x	y	z
Slow-4	ANCOVA
	L lingual gyrus	−27	−72	−3	0.117	1512
	R lingual gyrus	12	−90	−15	9.087	2646
	R middle frontal gyrus	57	18	33	6.876	1539
	R superior parietal lobule	27	−66	63	0.133	1890
	L superior frontal gyrus	−12	48	42	4.646	2943
	R superior frontal gyrus	36	0	36	3.465	5859
	CN vs. SCD
	R lingual gyrus	6	−90	−15	–4.076	324
	CN vs. naMCI
	R superior frontal gyrus	21	−15	60	–6.766	324
	CN vs. aMCI
	R middle frontal gyrus	51	30	30	4.418	1107
	L superior frontal gyrus	−18	48	36	3.350	432
	naMCI vs. aMCI
	L lingual gyrus	−3	−93	−6	3.898	297
Slow-5	ANCOVA
	R superior frontal gyrus	27	60	−6	6.964	3267
	R middle frontal gyrus	30	18	48	6.885	2187
	L superior parietal lobule/L precuneus	−24	−48	66	10.854	2889
	CN vs. aMCI
	R middle frontal gyrus	36	57	6	3.409	378
	SCD vs. aMCI
	R superior frontal gyrus	30	18	48	4.114	1404
	naMCI vs. aMCI
	L superior parietal lobule/L precuneus	−24	−48	66	5.298	1863

All significant results were presented in control of age, gender, and educational level with p < 0.05. TFCE-FWE correction was applied for voxel-wised two-sample T-test. To note, cluster size was set over 1,350 mm³ in ANCOVA analyses and over 270 mm³ in two-sample T-tests. CN, normal control; SCD, subjective cognitive decline; naMCI, non-amnestic mild cognitive impairment; aMCI, amnestic mild cognitive impairment; ALFF, amplitude of low-frequency fluctuation; ANCOVA, analysis of covariance; AAL, anatomical automatic labeling; MNI, Montreal Neurological Institute; R, right; L, left.