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. 2021 Feb 16;15:606600. doi: 10.3389/fnins.2021.606600

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Copyright © 2021 Lee, Yoon, Kim, Jeong, Seo, Na, Noh and Seong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subnetworks identified by correlation analyses between W-score networks and pathologies in (A) EOAD and (B) LOAD through cluster-based statistics. The factors used include global and regional THK retention in EOAD and global FLUTE retention, white matter hyperintensity volume, and lacunes in LOAD. Regional retention indicates the averaged retention between regions at both ends of an edge. The red circles are representative regions, with nodal degree exceeding the mean plus standard deviation of all nodal degrees. Edges within different clusters were displayed with different colors.