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. 2021 Jan 19;7(1):40–58. doi: 10.3934/microbiol.2021004

Table 2. Isolates were classified as susceptible (S) or resistant (R) based on the zones of inhibition (mm) observed; isolates that were resistant to at least one antimicrobial from three or more antimicrobial categories were classified as MDR [52].

Antibiotic Antimicrobial category Mode of action Disc content (µg) Zone diameter breakpoint (mm) [52]
S R
Ampicillin Beta-lactams Bacterial cell wall synthesis inhibitor 10 ≥16 <16
Chloramphenicol* Phenicols Inhibits protein synthesis (prevents growth) 30 ≥18 <18
Erythromycin Macrolides Inhibits protein synthesis (bacteriostatic) 15 ≥25 <25
Gentamicin* Aminoglycoside Inhibits protein synthesis (leads to cell death) 10 ≥18 <18
Tetracycline* Tetracycline Inhibits protein synthesis (ribosomal inhibitor) 30 ≥22 <19

*Breakpoints of Staphylococcus aureus ATCC 25923 were used to interpret the zones of inhibition [53],[57],[58].