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. 2021 Mar 1;11:4819. doi: 10.1038/s41598-021-84526-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Micro-CT 3D reconstruction image and quantitative analysis results of bone defect area 8 weeks after the injury. (A) Representative three-dimensional reconstruction image at 8 weeks after the injury. (B) Eight weeks after the surgery, the percentage of new bone volume in each group of bone defect segments *P < 0.05, **P < 0.01. (C) Bone mineral density analysis results of bone defect segments in each group at 8 weeks after surgery, *P < 0.05, **P < 0.01. Five samples were taken from each group for analysis, and the data were plotted in the format of mean ± standard deviation.