Table 2.

GO secondary annotations of proteins with downregulated p-site (WT vs. OE-GOLM1).

GO terms level 1	GO terms level 2	No. of protein
Biological process	Cellular process	276
	Biological regulation	232
	Single-organism process	229
	Metabolic process	167
	Cellular component organization or biogenesis	160
	Response to stimulus	148
	Multicellular organismal process	126
	Developmental process	120
	Localization	116
	Signaling	100
	Multi-organism process	56
	Immune system process	48
	Biological adhesion	30
	Locomotion	28
	Reproduction	25
	Other	28
Cellular component	Cell	305
	Organelle	268
	Membrane	191
	Macromolecular complex	110
	Membrane-enclosed lumen	110
	Extracellular region	87
	Cell junction	61
	Supramolecular complex	34
	Synapse	33
	Other	1
Molecular function	Binding	298
	Catalytic activity	95
	Molecular function regulator	32
	Structural molecule activity	28
	Signal transducer activity	22
	Molecular transducer activity	17
	Transcription factor activity, protein binding	17
	Transporter activity	17
	Nucleic acid binding transcription factor activity	16
	Other	3