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. 2021 Jan 31;27(1):39–47. doi: 10.4258/hir.2021.27.1.39

Figure 2.

Figure 2

Pipeline for receiving heterogeneous-longitudinal data, pseudonymization of PIDs for NICR and diagnostic imaging data, POSDA P-PIDs and PHI de-identification, and transformation into ARIES database for secondary data use. The pseudonymization algorithm is hosted in AR-CDR. The details of pseudonymization using AR-CDR data for both NICR pseudonymization (NICR-P) and radiologic image pseudonymization (RIP) requests is shown in Figure 3. The “Pseudonymization Layer” represents O-CAPP’s framework to receive PIDs, execute the pseudonymization algorithm, and return P-PIDs. The process is presented in detail in Figure 4. The blue dotted line represents de-identified research data in ARIES that can be linked back to fully identified AR-CDR data using the mappings maintained in AR-CDR and POSDA. PID: participant identifiers, P-PID: pseudonyms of participant identifiers, AR-CDR: Arkansas Clinical Data Repository, POSDA: Perl Open-Source Digital Imaging and Communications in Medicine Archive, NICR: non-imaging clinical research, ARIES: Arkansas Image Enterprise Systems, PHI: protected health information, O-CAPP: participant identifier pseudonymization, PACS: picture archiving and communication system, DICOM: Digital Imaging and Communications in Medicine.