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. 2020 Jun 2;41(12):1547–1556. doi: 10.1038/s41401-020-0409-3

Fig. 5. ICS II increased TIMP1 expression in cerebral I/R-induced injury.

Fig. 5

a Representative images of immunohistochemical staining of TIMP1 in the cortex and striatum. b Quantitative analysis of TIMP1 in the cortex and striatum. c Representative images of immunoblotting of TIMP1 in the penumbra. d Quantitative analysis of TIMP1 in the penumbra. e Quantitative analysis of active MMP9/TIMP1 in the penumbra. f Quantitative analysis of active MMP2/TIMP1 in the penumbra. Five random microscope fields per section were chosen. The average was calculated. **P < 0.01 vs sham; #P < 0.05, ##P < 0.01 vs MCAO; n = 6 per group.