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. 2021 Mar 1;11:4835. doi: 10.1038/s41598-021-83668-1

Table 2.

Gatekeepers: Enrichment test-Reactome pathways. Main reactome pathways are shown if False discovery rate value was less than 0.05.

Reactome pathways Homo sapiens—REFLIST (20,851) Client Text Box Input (27) Client Text Box Input (over/under) Client Text Box Input (FDR)
Unwinding of DNA (R-HSA-176974) 12 2 + 2.07E−02
Deposition of new CENPA-containing nucleosomes at the centromere (R-HSA-606279) 54 3 + 1.23E−02
Nucleosome assembly (R-HSA-774815) 54 3 + 1.12E−02
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (R-HSA-141444) 92 4 + 1.55E−02
Amplification of signal from the kinetochores (R-HSA-141424) 92 4 + 7.76E−03
Mitotic Spindle Checkpoint (R-HSA-69618) 108 4 + 7.15E−03
EML4 and NUDC in mitotic spindle formation (R-HSA-9648025) 114 4 + 7.03E−03
Chromosome Maintenance (R-HSA-73886) 90 3 + 3.11E−02
Resolution of Sister Chromatid Cohesion (R-HSA-2500257) 122 4 + 7.59E−03
RHO GTPases Activate Formins (R-HSA-5663220) 135 4 + 8.37E−03
Separation of Sister Chromatids (R-HSA-2467813) 185 4 + 1.85E−02
Mitotic Anaphase (R-HSA-68882) 193 4 + 2.00E−02
Mitotic Metaphase and Anaphase (R-HSA-2555396) 194 4 + 1.89E−02
Mitotic Prometaphase (R-HSA-68877) 198 4 + 1.91E−02
Cell Cycle Checkpoints (R-HSA-69620) 270 5 + 7.94E−03
Cell Cycle, Mitotic (R-HSA-69278) 495 6 + 9.07E−03
Cell Cycle (R-HSA-1640170) 600 7 + 6.91E−03