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. 2020 Nov 23;124(5):862–879. doi: 10.1038/s41416-020-01156-1

Fig. 4. Protein s-cysteinylation.

Fig. 4

The oxidation of a cysteine residue within a protein can result in the formation of a cysteinyl radical. l-Cystine is reduced to l-cysteine under the action of l-cystine reductase. Reaction between protein cysteinyl residues and low molecular weight thiols such as free cysteine can yield s-cysteinylated proteins.