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. 2021 Mar 1;11:4816. doi: 10.1038/s41598-021-84352-0

Table 1.

Demographic characteristics, stratified by HIV status, RADAR, Chicago 2015–2017.

Variable Total (N = 684) HIV positive (n = 195) HIV negative (n = 489) p
n/mean %/SD n/mean %/SD n/mean %/SD
Age, mean (SD) 22.8 4.8 25.0 4.3 22.0 4.7  < 0.001
BMI, mean (SD) 25.4 6.0 24.9 5.2 25.6 6.3 0.170
Race/ethnicity, n (%)  < 0.001
White 157 23.0 7 3.6 150 30.7
Black 292 42.7 127 65.1 165 33.7
Hispanic/Latinx 203 29.7 44 22.6 159 32.5
Other 32 4.7 17 8.7 15 3.1
Education, n(%) 0.259
 < High school 100 14.7 23 11.8 77 15.8
High school/GED 165 24.2 56 28.7 109 22.4
Some college 334 49.0 92 47.2 242 50.0
 ≥ Bachelor’s 83 12.2 24 12.3 59 12.1
Sexual orientation, n (%) 0.003
Gay 483 70.8 155 79.5 328 67.4
Bisexual 134 20.0 23 11.8 111 22.8
Other 65 9.5 17 8.7 48 9.9
Gender identity, n(%) 0.007
Male 624 91.5 172 88.2 452 92.8
Transgender woman 47 6.9 22 11.3 25 5.2
Other 11 1.6 1 0.5 10 2.1
Marijuana use frequency, n (%) 0.002
Never 266 39.0 62 31.8 204 41.9
Intermittent 159 23.3 39 20.0 120 24.6
Frequent 257 37.7 94 48.2 163 33.5
Positive rectal STI test, n(%)
Gonorrhea 68 10.2 40 21.4 28 5.8  < 0.001
Chlamydia 83 12.4 40 21.3 43 8.9  < 0.001
Drug and alcohol use
Self-reported substance use1
Marijuana 491 72.0 144 73.9 347 71.3 0.496
Poppers 108 15.8 32 16.4 76 15.6 0.795
Cocaine/crack 100 14.7 37 19.0 63 12.9 0.044
Ecstasy 75 11.0 25 12.8 50 10.3 0.335
Psychedelics 28 4.1 1 0.5 27 5.5 0.003
Other drug use2 46 6.7 19 9.7 27 5.5 0.047
Urine drug screen positive3
Marijuana 297 44.1 127 65.8 170 35.3  < 0.001
Cocaine/crack 38 5.7 23 11.9 15 3.1  < 0.001
Ecstasy/MDMA 9 1.3 6 3.1 3 0.6 0.011
Other drug use4 51 7.5 28 14.4 23 4.7  < 0.001
AUDIT4, mean (SD) 6.0 5.7 5.8 6.2 6.1 5.5 0.437
CUDIT4, mean (SD) 6.4 6.4 7.3 6.5 6.1 6.3 0.017
Tobacco use5, n(%) 292 42.8 106 54.4 186 38.2  < 0.001
Biologic markers
Unadjusted CRP (mg/L), mean (SD) 3.9 8.5 5.7 9.8 3.3 7.9  < 0.001
Log-transformed CRP, mean (SD) 0.2 1.6 0.8 1.5 0.02 1.6  < 0.001
Detectable HIV viral load6 102 76.1

BMI = body mass index; STI = sexually transmitted infection; CRP = C-reactive protein.

1In the past six months.

2Other drug use includes: methamphetamines, synthetic marijuana, ketamine, GHB, inhalants, heroin.

3Note: urine drug screens unavailable for poppers and psychedelics; other urine drug screen includes: benzodiazepines, amphetamines, methamphetamines, opiates.

4Based on the Alcohol Use Disorders Identification Test (AUDIT) and Cannabis Use Disorders Identification Test (CUDIT) scoring methods; higher score indicates higher risk alcohol use.

5In the past 30 days.

6Detectable viral load defined as ≥ 50 copies/mL; viral load data available on 134 participants only.