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. 2021 Feb 16;11:578831. doi: 10.3389/fphar.2020.578831

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Copyright © 2021 Tseng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier curves comparing hemorrhoid-free probability in never users and ever users of metformin in the unmatched cohort (A) and the matched cohort (B). HR: hazard ratio, CI: confidence interval.