TABLE 1.

Hyperparameter values used in the Random Forest and XGBoost analyses.

	RF (threefold CV)	XGBoost (threefold CV)
Adrenal gland	Mtry = 0.1 × M	Colsample = 0.01
	Ntree = 2,000,000	Eta = 0.5
Hypothalamus	Mtry = sqrt (M)	Colsample = 0.01
	Ntree = 2,000,000	Eta = 0.5
Liver	Mtry = sqrt (M)	Colsample = 0.01
	Ntree = 1,000,000	Eta = 0.01
Muscle	Mtry = sqrt (M)	Colsample = 0.01
	Ntree = 1,000,000	Eta = 0.01
Pituitary	Mtry = 0.1 × M	Colsample = 0.03
	Ntree = 2,000,000	Eta = 0.01

M, total number of genes in individual tissue; Ntree, number of trees; Mtry, number of genes for forming a decision tree; colsample, proportion of genes subsampled for a decision tree; eta, learning rate; CV, cross validation.