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. 2021 Feb 16;12:623424. doi: 10.3389/fgene.2021.623424

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Copyright © 2021 Zhou, Xie, Wang, Zhang, Li, Sun, Cai, Wu, Dang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune-related genes and relations with colon cancer prognosis. (A) Venn plot shows core immune genes between the Immport and TCGA database. (B) Hazard ratio was analyzed among 24 identified immune-related genes by univariate Cox regression analysis. Two hub genes (CHGB and SCT) indicated significant difference in survival of colon cancer patients. (C) Immune risk score calculated for each colon cancer patients. Patients were divided into high risk and low risk group by median risk score. (D) The survival time of different colon cancer patients. (E) Low immune risk group showed better 5-year survival than High risk group.