Figure 4.

NIR-fluorescence imaging of mouse brain before and after treatment with PbS QDs

(A–C) (A) Experimental setup for NIR fluorescence imaging of cerebral blood vessels. An anesthetized mouse was administered QD1100 (PbS QDs) in a caudal vein. An optical laser (785 nm wavelength) was used as an excitation light source, and NIR fluorescence was detected with an InGaAs camera. (B) Imaging of a mouse head. Bright field image (left), NIR fluorescence image without QD administration (middle), and the NIR fluorescence image with QD administration (right). Scale bar: 1 mm. (C) NIR fluorescence images of cerebral blood vessels. Upper: fluorescence image after scalp removed; lower: fluorescence image after isolation. Scale bars: 1 mm. Adapted with permission from (Imamura et al., 2016).