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. 2021 Feb 17;5(3):33–36. doi: 10.15698/cst2021.03.244

Figure 1. FIGURE 1: The centrosomal protein OFD1 controls autophagy.

Figure 1

OFD1 promotes the selective autophagy-mediated degradation of ATG13, a component of ULK1 autophagy initiation complex. Loss of OFD1 determines ULK1 complex enhanced protein stability associated with excessive autophagy (Adapted from Morleo M et al. (2020), EMBO J, doi: 10.15252/embj.2020105120).