Fig. 3.

Inhibition of PM₁₀-induced CYP1A1 by LL, LL-EA and oleanolic acid in keratinocytes. (A) HaCaT was pre-treated with different concentrations of LL 20 μg/mL for 6 h, and after that PM₁₀ (50 μg/mL) was treated for 3 h and analyzed by RT-PCR. (B) HaCaT was pre-treated with different concentrations of LL-EA (2.5, 5, 10 μg/mL) for 6 h, and after that PM₁₀ (50 μg/mL) was treated for 3 h and analyzed by RT-PCR. (C) HaCaT was pre-treated with different concentrations of oleanolic acid (2.5, 5, 10 μg/mL) for 6 h, and and after that PM₁₀ (50 μg/mL) was treated for 3 h and analyzed by RT-PCR. Histograms of quantitated mRNA expression were showed in (D-F).