Figure 2.

miRNA expression in plasma of surgery naïve Stage IV CRC patients compared to those recently postoperative and those recurrent (meaning newly diagnosed Stage IV CRC previously undergone bowel resection surgery at early stage CRC). (a) Significantly dysregulated miRNA (b) Non-significantly dysregulated miRNA. Whiskers represent minimum and maximum, the top, the bottom, and the band in the box represent the first and third quartile and the median respectively. * above boxplots denotes p-value < 0.05 according to Wilcoxon’s signed-rank test. * above line denotes p-value < 0.05 and ** above line denotes <0.01 according to Kruskal Wallis test when comparing all subgroups and to Mann–Whitney test when comparing 2 subgroups.