Neuropharmacological effect of EaF-SF (200 and 400 mg/kg) on mice. Anxiolytic activity by elevated plus maze (A) and hole board test (B), anti-depressant activity by forced swimming test (C), and locomotor activity by open field test (D). Values are represented as Mean ± SEM (n = 6 per group). * p < 0.05, ** p < 0.01, and *** p < 0.001 are statistically significant in comparison to Tween-80 (Control: 10 mL/kg) followed by one-way analysis of variance (ANOVA, Dunnett’s test). Here, EaF-SF: Ethyl acetate fraction of Syzygium fruticosum; Reference drug: diazepam (1 mg/kg) and fluoxetine (10 mg/kg).