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. 2021 Feb 19;13(4):624. doi: 10.3390/polym13040624

Table 1.

Summary of key pH-labile linkages for the development of cleavable functionalities.

Representative Structure 1 pH-Responsive Component Ref(s)
graphic file with name polymers-13-00624-i001.jpg Amide [9,61,62,63,64]
graphic file with name polymers-13-00624-i002.jpg Anhydride [65]
graphic file with name polymers-13-00624-i003.jpg Hydrazone [66,67,68,69]
graphic file with name polymers-13-00624-i004.jpg Acetal [70]
graphic file with name polymers-13-00624-i005.jpg Imine [71]
graphic file with name polymers-13-00624-i006.jpg Ketal [72]

1 pH-cleavable linker highlighted in blue.