Table 3.
Uremic toxins according to UBF and placebo arms during the follow-up of patients undergoing peritoneal dialysis (n = 26).
Variables | UBF | Placebo | p | ||
---|---|---|---|---|---|
Pre | Post | Pre | Post | ||
Serum total uremic toxins (μmol/L) | |||||
IS | 67 (35–141) | 63 (35–139) | 59 (37–137.5) | 72.7 (32.5–136) | 0.70 |
pCS | 153.5 (88–283) | 171.5 (131–263) | 149.5 (95–235) | 164 (108–242) | 0.70 |
IAA | 8.7 (5.7–13.4) | 9 (6–15) | 9.7 (5.3–13) | 8 (5.8–13.2) | 0.74 |
Serum free uremic toxins (μmol/L) | |||||
IS | 1.4 (0.6–4.3) | 1.6 (0.7–3.5) | 1.7 (0.8–4.2) | 1.5 (0.7–3.1) | 0.95 |
pCS | 1.8 (0.9–4.7) | 2.2 (1–5.5) | 2.3 (1–5) | 2.3 (1.1–4.6) | 0.24 |
IAA | 0.60 (0.2–1.1) | 0.65 (0.3–1) | 0.68 (0.25–1) | 0.62 (0.3–0.8) | 0.29 |
Urinary total uremic toxins (μmol/24 h) | |||||
IS | 200 (130–290) | 199 (64–263) | 210 (87–273) | 180 (105–285) | 0.36 |
pCS | 97 (30–184) | 100 (48–286) | 117 (49–240) | 97 (39–222) | 0.25 |
IAA | 5.7 (2.9–8.6) | 5.2 (2.7–11.3) | 3.6 (2.5–9.3) | 3.9 (2.3–7.6) | 0.55 |
Dialysate total uremic toxins (μmol/24 h) | |||||
IS | 30 (14–78) | 29 (15–76) | 33.4 (19–68) | 28.4 (19–88) | 0.45 |
pCS | 24 (10–139) | 28 (12–88) | 30.4 (10–98) | 25 (12–85) | 0.90 |
IAA | 8.3 (5–18) | 10 (5–19) | 11.4 (6–19) | 11 (6–15) | 0.82 |
Data are presented as mean ± SD or as the median (interquartile range). IS—indoxyl sulfate; pCS—p-cresyl sulfate; IAA—indole 3-acetic acid.