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. 2021 Feb 19;22(4):2072. doi: 10.3390/ijms22042072

Table 1.

Number of genes in the human genome as of 2021.

Type GENCODE [5] NCBI [6] Ensemble [7] Genecards [8]
Total number of genes 60,660 54,644 59,662 270,168
Protein-coding genes 19,962 20,203 20,448 20,916
Genes that have more than one distinct translation 13,685 * 20,110 * n.a. n.a.
Non-coding genes n.a. 17,871 23,997 219,587
lncRNA genes 17,958 n.a. n.a. 75,839 *
Small ncRNA/pir ncRNA genes 7569 n.a. n.a. 109,820 *
Pseudogenes 14,761 15,067 15,217 21,888
Others 350 1503 n.a. 7777

The fields with * indicate that they have not been summarized into the total number of genes.