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. 2021 Feb 17;22(4):1981. doi: 10.3390/ijms22041981

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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SMUG1 and cancer development and progression. The relationship between SMUG1 expression and cancer progression. (A) Effects of Smug1^−/− Ung^−/− Msh2^−/− on mice survival from [45] with permission. (B) Smug1^−/− has protective effect to treatment with 5-hmdU, from with [45] permission. Summary of the search of The Human Protein Atlas for SMUG1 in the pathology section. Prognostic analysis of patient survival in (C) ovarian and (D) liver cancers. Low mRNA expression (blue) compared to high (pink) mRNA expression levels of SMUG1, analysis reached high significance [46].