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Schematic representation of Hippo signaling pathway in OC (A) The main genes involved in Hippo signaling as regards OC and the associated miRNAs. As shown, miR-25-3p target TP53, TEF, LATS1, LATS2, and miR-181c target TEF, LATS1, LATS2, and MST1, respectively. (B) Relative expression levels of the main genes involved in Hippo signaling pathway in OC, TT (tumor tissue) versus TN (normal tissue) (C) schematic representation of the OC tumor microenvironment.
