Table 7.
Logistic regression analysis of PVT1, HOTAIR, NEAT1, MALAT1, PAI-1, and OPN to predict breast cancer risk.
| Parameter (Control) | Coefficient (β) | SE | Wald (x2) | p-Value | Odds Ratio | 95% CI |
|---|---|---|---|---|---|---|
| Univariate Analysis | ||||||
| PVT1 | 0.62 | 0.26 | 5.63 | 0.018 * | 1.86 | 1.11–3.12 |
| HOTAIR | 0.58 | 0.26 | 5.04 | 0.02 * | 1.79 | 1.07–3.00 |
| NEAT1 | 0.01 | 0.12 | 0.002 | 0.967 | 0.99 | 0.775–1.27 |
| MALAT1 | 0.16 | 0.12 | 1.70 | 0.192 | 1.17 | 0.92–1.50 |
| PAI-1 | 0.63 | 0.16 | 14.67 | 0.0008 ** | 1.88 | 1.36–2.59 |
| OPN | 0.15 | 0.04 | 13.86 | 0.001 ** | 1.07 | 1.07–1.26 |
| Multivariate Analysis | ||||||
| PAI-1 | 0.44 | 0.15 | 7.99 | 0.01 * | 1.56 | 1.14–2.12 |
* Significance at p < 0.05; ** significance at p < 0.001; PVT1, plasmacytoma variant translocation 1 gene; HOTAIR, HOX transcript antisense RNA; NEAT1, nuclear enriched abundant transcript 1; MALAT1, metastasis associated lung adenocarcinoma transcript 1; PAI-1, plasminogen activator inhibitor-1; OPN, osteopontin; SE, standard error.