Figure 3.

Ex vivo expansion of NK cells leads to a highly significant transcriptional alterations in genes that govern cellular trafficking. (A) Bubble plots that displays genes that control NK in vivo trafficking; Graphical organization is the same as in Figure 2A. (B) Heat maps that report FPKM values for the genes that are graphed in (A). (C) Line graphs showing the change in transcription of genes that regulate CXCR4 in NK cells from fresh (F) to expanded with either LCL feeder cells (L) or GE-K562 feeder cells (K), from individual donors. The paired t-test was used to determine significance, ns = not significant, * p < 0.05, ** p < 0.01, *** p < 0.001.