Table 2. Number of Adverse Drug-Related Incidents, ADEs, and Clinically Important Medication Errors During the First 45 Days After Hospital Discharge by Treatment Assignment.
Characteristic | Events, No.a | IRR (95% CI) | ||||||
---|---|---|---|---|---|---|---|---|
Total | Intervention | Control | Unadjusted | Adjustedb | ||||
No. | IR | No. | IR | No. | IR | |||
All adverse drug-related incidents | 153 | 1.03 | 81 | 1.10 | 72 | 0.97 | 1.13 (0.83-1.56) | 0.97 (0.70-1.34) |
ADEs | 130 | 0.88 | 68 | 0.92 | 62 | 0.83 | 1.11 (0.78-1.56) | 0.96 (0.68-1.37) |
Clinically important medication errorsc | 89 | 0.60 | 44 | 0.60 | 45 | 0.60 | 0.99 (0.65-1.49) | 0.81 (0.53-1.23) |
Preventable/ameliorable ADEs | 66 | 0.44 | 31 | 0.42 | 35 | 0.47 | 0.89 (0.55-1.45) | 0.74 (0.45-1.22) |
Potential ADEs | 23 | 0.15 | 13 | 0.18 | 10 | 0.13 | 1.31 (0.57-2.99) | 1.02 (0.44-2.36) |
Serious/life-threatening preventable/ameliorable ADEs | 17 | 0.11 | 7 | 0.09 | 10 | 0.13 | 0.71 (0.27-1.85) | 0.53 (0.20-1.39) |
Abbreviations: ADE, adverse drug event; IR, incidence rate per 100 patient-days of observation; IRR, incidence rate ratio.
Based on 180 patients in the intervention group contributing 7392 days of observation and 181 patients in the control group contributing 7447 days of observation. Patients could experience more than 1 event.
Models included age, sex, and having visiting nurse services.
Clinically important medication errors are a composite of preventable/ameliorable ADEs and potential ADEs.