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. 2021 Mar 1;181(5):610–618. doi: 10.1001/jamainternmed.2020.9285

Table 2. Number of Adverse Drug-Related Incidents, ADEs, and Clinically Important Medication Errors During the First 45 Days After Hospital Discharge by Treatment Assignment.

Characteristic Events, No.a IRR (95% CI)
Total Intervention Control Unadjusted Adjustedb
No. IR No. IR No. IR
All adverse drug-related incidents 153 1.03 81 1.10 72 0.97 1.13 (0.83-1.56) 0.97 (0.70-1.34)
ADEs 130 0.88 68 0.92 62 0.83 1.11 (0.78-1.56) 0.96 (0.68-1.37)
Clinically important medication errorsc 89 0.60 44 0.60 45 0.60 0.99 (0.65-1.49) 0.81 (0.53-1.23)
Preventable/ameliorable ADEs 66 0.44 31 0.42 35 0.47 0.89 (0.55-1.45) 0.74 (0.45-1.22)
Potential ADEs 23 0.15 13 0.18 10 0.13 1.31 (0.57-2.99) 1.02 (0.44-2.36)
Serious/life-threatening preventable/ameliorable ADEs 17 0.11 7 0.09 10 0.13 0.71 (0.27-1.85) 0.53 (0.20-1.39)

Abbreviations: ADE, adverse drug event; IR, incidence rate per 100 patient-days of observation; IRR, incidence rate ratio.

a

Based on 180 patients in the intervention group contributing 7392 days of observation and 181 patients in the control group contributing 7447 days of observation. Patients could experience more than 1 event.

b

Models included age, sex, and having visiting nurse services.

c

Clinically important medication errors are a composite of preventable/ameliorable ADEs and potential ADEs.