Table 3. Frequency of Types of Adverse Drug Events.
| Type of eventa | No. (%) | ||
|---|---|---|---|
| Overall (N = 130) | Intervention (n = 68) | Control (n = 62) | |
| Gastrointestinal | 41 (31.54) | 19 (27.94) | 22 (35.48) |
| Cardiovascular | 28 (21.54) | 14 (20.59) | 14 (22.58) |
| Kidney/electrolytes/fluid balance | 20 (15.38) | 9 (13.24) | 11 (17.74) |
| Hemorrhagic | 14 (10.77) | 7 (10.29) | 7 (11.29) |
| Metabolic or endocrine | 11 (8.46) | 7 (10.29) | 4 (6.45) |
| Dermatologic | 10 (7.69) | 6 (8.82) | 4 (6.45) |
| Neuropsychiatricb | 10 (7.69) | 9 (13.24) | 1 (1.61) |
| Syncope or dizziness | 8 (6.15) | 2 (2.94) | 6 (9.68) |
| Infection | 3 (2.31) | 1 (1.47) | 2 (3.23) |
| Fall without injury | 2 (1.54) | 2 (2.94) | 0 |
| Fall with injury | 1 (0.77) | 0 | 1 (1.61) |
| Hematologic | 1 (0.77) | 0 | 1 (1.61) |
| Respiratory | 1 (0.77) | 1 (1.47) | 0 |
| Other | 5 (3.85) | 1 (1.47) | 4 (6.45) |
| Inadequate pain control | 2 (1.54) | 0 | 2 (3.23) |
| Myalgia | 1 (0.77) | 1 (1.47) | 0 |
| Night sweats | 1 (0.77) | 0 | 1 (1.61) |
| Nonspecific drug intolerance | 1 (0.77) | 0 | 1 (1.61) |
a
Adverse drug events could manifest as more than 1 type.
b
Neuropsychiatric events include oversedation, confusion, hallucinations, and delirium. Adverse drug events could manifest as more than 1 type.