Table 4.
Adjusted means of demographic characteristics of the participants according to polygenetic risk scores (PRSs) related to collagen metabolism.
| Low PRS a (n = 25) |
Medium PRS (n = 48) |
High PRS (n = 55) |
|
|---|---|---|---|
| Age (yrs) | 52.4 ± 2.27 | 50.3 ± 1.61 | 53.1 ± 1.50 |
| Menopause (Yes, %) | 13 (52.0) | 19 (39.6) | 23 (41.8) |
| UV exposure (Yes, %) | 9 (36.0) | 7 (35.4) | 24 (43.6) |
| Sunscreen usage (No, %) | 16 (64.0) | 31 (64.6) | 31 (56.4) |
| Water intake (cups/day) | 2.89 ± 0.56 | 3.59 ± 0.40 | 3.87 ± 0.37 |
| Coffee intake (cups/day) | 1.06 ± 0.36 | 0.95 ± 0.25 | 1.26 ± 0.23 |
| Alcohol intake (Yes, %) | 13 (52.0) | 29 (60.4) | 29 (52.7) |
| Fruit intake (serving/day) | 1.93 ± 0.17 | 0.95 ± 0.25 | 1.26 ± 0.23 |
| Vitamin supplementation (Yes, %) | 20 (80.0) | 31 (64.6) | 36 (65.5) |
| Smoking (Yes, %) | 1 (4.0) | 2 (4.2) | 2 (3.6) |
| Exercise (Yes, %) | 9 (36.0) | 29 (60.4) | 37 (67.3) |
| Sleep deprivation (Yes, %) | 5 (20.0) | 18 (37.5) | 25 (45.5) |
| Tiredness after awakening (Yes, %) | 19 (76.0) | 27 (56.3) | 44 (80.0) |
The values represent adjusted means ± standard deviations or the number of subjects (percentage of each group). PRS was generated by summing the number of the risk alleles in the collagen type XVII alpha 1 chain (COL17A1) rs805698, epidermal growth factor receptor (EGFR) rs1861003, and matrix metalloproteinase 16 (MMP16) rs6469206. a PRS ≤ 1, low PRS; 2–3 PRS, medium PRS; PRS ≥ 4, high PRS.