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. 2021 Feb 18;22(4):2027. doi: 10.3390/ijms22042027

Figure 1.

Figure 1

Role of the pro-inflammatory environment and tissue inflammation in CD. Pro-inflammatory environment has an important role in CD pathogenesis. It can be induced by external factors that can be specific for CD cells such as the A-gliadin peptide P31–43, or not specific (infections, diet, other wheat components etc.), but it can also be constitutive in the CD cells.