Figure 7.

Timeline of AdipoRon treatment and behavioral tests. Before AdipoRon treatment, mice received three doses of BrdU injections (50 mg/kg i.p.) to study newborn cell survival. Mice have received AdipoRon treatment (20 or 50 mg/kg i.p.) or vehicle treatment continuously for 14 days. The day after, mice were subjected to the open field test and the Y-maze task on two consecutive days. The day after the Y-maze test, mice were sacrificed to collect blood samples for ELISA and fixed brain tissues for immunostaining.