Figure 5.

Tumour weight was evaluated following treatment with Uncaria tomentosa. Animals were injected with B16-BL6 tumour cells and then received intraperitoneal (IP) or intra-tumour (IT) injections with Uncaria tomentosa, extracted with 70% ethanol (EtOH) or PBS, pH 7.4, (PBS) that had been freeze-dried and resuspended in PBS. At endpoint, the mice were euthanised and the tumours were removed to determine the tumour diameters (size) and weights, and the mouse body weights. The average measures for each of the five treatment groups was plotted using a box and whisker plot (whiskers are 95% interval) for the (A) combined experiments (n = 8–10) or (B) two separate experiments (n = 4–5). The results revealed that there were significant differences (p < 0.05) between each of the four treated groups compared to the control (*) using ANOVA and Tukey post hoc statistical analysis.