Table 3.
List of proteins identified in at least two studies, not concerning repair foci.
| Priority Group | Author, Date | Marker | Outcome | Cell System |
|---|---|---|---|---|
| 1 | Braicu, 2014 | VEGFA | decrease in VEGFA concentration leads to increase in survival, >500 pg/mL negative influence on survival | Serum |
| Fekete, 2015 | VEGFA | nr | MSCs | |
| Nguyen, 2019 | VEGFA | resistant compared to Treg | CCR6 + Th17 | |
| 2 | Cao, 2011 | Caspase 3 # | radiosensitive | CD4 + CD25 + Treg cells |
| Nguyen, 2019 | Caspase 3 | resistant compared to Treg | CCR6 + Th17 | |
| 2 | Miyake, 2019 | p16 | resistant compared to primary fibroblasts (IR-induced senescence) | NB1RGB KCs 1stP, 2ndP and 3rdP |
| Nguyen, 2019 | p16 | resistant compared to Treg (IR-induced senescence) | CCR6 + Th17 | |
| 2 | Cao, 2011 | IL-6 | radiosensitive | CD4 + CD25 + Treg cells |
| Fekete, 2015 | IL-6 | nr | MSCs | |
| 2 | Cao, 2011 | IL-1Beta | radiosensitive | CD4 + CD25 + Treg cells |
| Nguyen, 2019 | IL-1Beta | sensitive compared to CCR6 + Th17 | CCR6negTh |
# higher increase in sensitive cells, proteins upregulated post-IR shown in orange, downregulation in blue, and no change in black.