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. 2021 Feb 18;13(2):314. doi: 10.3390/v13020314

Figure 3.

Figure 3

Bunyavirales Genome Organization. Specific genome structures for Bunyavirales families containing human pathogens, including Arenaviridae, Peribunyaviridae, Nairoviridae, Hantaviridae, and Phenuiviridae [5,12,13,14,15,16,17,18,19], are shown. The reference strain for each family is listed as well as the approximate size of each genomic segment. Glycoprotein precursor (GPC), nucleoprotein (NP), intergenic region (IGR), zinc-binding matrix protein (Z), non-structural S segment protein (NSs), non-structural M segment protein (NSm), surface glycoproteins (Gn and Gc), mucin-like domain (MLD), and secreted glycoprotein (GP38). NS proteins are highlighted in dark blue and include NSs and NSm, along with MLD and GP38 for Nairoviridae. The L segment is not as well understood as S and M and has many regions with unknown function but, across the order encodes the RNA-dependent RNA-polymerase (RdRp) gene.