Table 3.

Preoperative and Postoperative Medications Compared by Mixed-Effects Regression Model.

Periods	Total			µLOT Alone			µLOT + Cataract Surgery
	No. Eyes	Mean ± SD (Range)	p Value ‡	No. Eyes	Mean ± SD (Range)	p Value ‡	No. Eyes	Mean ± SD (Range)	p Value ‡
Preoperative	560	2.8 ± 1.1 (0, 6)		159	3.3 ± 1.1 (0, 6)		401	2.7 ± 1.1 (0, 5)
3 days	546	2.4 ± 1.0 (0, 5)	<0.0001	152	2.8 ± 0.9 (0, 4)	<0.0001	394	2.3 ± 1.0 (0, 5)	<0.0001
1–2 weeks	544	2.4 ± 0.9 (0, 4)	<0.0001	155	2.7 ± 0.8 (0, 4)	<0.0001	389	2.3 ± 1.0 (0, 4)	<0.0001
1 month	497	2.5 ± 0.9 (0, 5)	<0.0001	137	2.7 ± 0.9 (0, 5)	<0.0001	360	2.4 ± 0.9 (0, 4)	<0.0001
3 months	427	2.4 ± 0.9 (0, 4)	<0.0001	116	2.7 ± 0.9 (0, 4)	<0.0001	311	2.3 ± 0.9 (0, 4)	<0.0001
6 months	362	2.4 ± 1.0 (0, 5)	<0.0001	96	2.8 ± 0.9 (0, 5)	<0.0001	266	2.3 ± 0.9 (0, 4)	<0.0001
9 months	303	2.4 ± 0.9 (0, 4)	<0.0001	85	2.8 ± 0.8 (1, 4)	<0.0001	218	2.3 ± 0.9 (0, 4)	<0.0001
12 months	263	2.5 ± 0.9 (0, 4)	<0.0001	65	2.8 ± 0.8 (1, 4)	0.0007	198	2.4 ± 0.9 (0, 4)	0.0004
18 months	200	2.6 ± 0.9 (0, 4)	0.0052	53	2.9 ± 0.8 (1, 4)	0.0053	147	2.5 ± 0.9 (0, 4)	0.0472
24 months	127	2.5 ± 1.0 (0, 4)	0.0191	37	2.9 ± 0.8 (1, 4)	0.0007	90	2.3 ± 1.0 (0, 4)	0.5559
30 months	74	2.5 ± 0.9 (1, 4)	0.0918	21	2.7 ± 1.0 (1, 4)	0.0014	53	2.4 ± 0.9 (1, 4)	1.0000
36 months	47	2.4 ± 1.0 (1, 4)	0.2612	12	2.6 ± 1.2 (1, 4)	0.0069	35	2.4 ± 0.9 (1, 4)	0.6378
Final visit	548	2.5 ± 1.0 (0, 5)	<0.0001	157	2.8 ± 0.9 (0, 5)	<0.0001	391	2.4 ± 1.0 (0, 5)	<0.0001
		p < 0.0001 †			p < 0.0001 †			p < 0.0001 †

Data are expressed as means ± standard deviations (range). † p values are calculated using the mixed-effects regression model. ‡ p values are calculated using the paired t-test between preoperative and respective time period values. Abbreviations: µLOT, microhook trabeculotomy; SD, standard deviation.