Table 3.
Effects on microbial community composition at the family level in the distal colon. Abundance (log counts/mL) of microbial families in the luminal environment of the distal colon (DC) of the human gastrointestinal tract at the end of the control (C; n = 3/donor) and the treatment (TR; n = 3/donor) period upon treatment with OFO at a dose of 1.4 g/d and POF at a dose of 1.4 g/d for three human donors tested. For optimal observation of consistent effects over the different donors tested, the average of the three donors is presented (n = 3). The intensity of the shading correlates with the absolute abundance, which was normalised for each of the different families. Statistically significant differences relative to the control period are indicated in bold (p < 0.05). Statistically significant differences between the different test products (i.e., TR–POF versus TR–OFO) are indicated with different letters (a, b), with conditions not sharing a similar letter being significantly different from each other (p < 0.05).
| Distal Colon | |||||
|---|---|---|---|---|---|
| POF | OFO | ||||
| C | TR | C | TR | ||
| Actinobacteria | Bifidobacteriaceae | 7.39 | 8.26 | 7.45 | 8.13 |
| Coriobacteriaceae | 5.61 | 5.31 | 5.66 | 4.93 | |
| Bacteroidetes | Bacteroidaceae | 8.35 | 8.20 | 8.30 | 8.04 |
| Muribaculaceae | 5.26 | 6.23 | 4.87 | 6.02 | |
| Prevotellaceae | 6.55 | 6.95 | 6.27 | 7.22 | |
| Rikenellaceae | 6.29 | 5.74 | 6.12 | 6.10 | |
| Tannerellaceae | 7.26 | 7.84 | 7.28 | 7.64 | |
| Firmicutes | Acidaminococcaceae | 6.61 | 7.22 | 6.79 | 6.94 |
| Enterococcaceae | 4.39 | 6.11 | 4.34 | 7.88 | |
| Erysipelotrichaceae | 5.64 | 4.86 | 5.65 | <LOD | |
| Lachnospiraceae | 8.23 | 8.28 | 8.16 | 8.27 | |
| Lactobacillaceae | 4.53 | 8.25 | 4.45 | 6.76 | |
| Ruminococcaceae | 6.64 | 6.12 | 6.74 | 5.90 | |
| Veillonellaceae | 7.37 | 8.04 | 7.34 | 7.36 | |
| Fusobacteria | Fusobacteriaceae | 5.62 | 6.34 | 5.70 | 7.66 |
| Proteobacteria | Burkholderiaceae | 6.48 | 6.73 | 6.52 | 6.31 |
| Desulfovibrionaceae | 6.58 | 6.79 | 6.76 | 6.94 | |
| Enterobacteriaceae | 5.42 | 6.36 | 5.45 | 7.63 | |
| Pseudomonadaceae | 6.57 | 5.52 | 6.44 | 6.48 | |
| uncultured | 5.89 | 6.51 | 6.05 | 6.33 | |
| Synergistetes | Synergistaceae | 6.93 | 7.52 | 7.16 | 7.27 |
| Verrucomicrobia | Akkermansiaceae | 7.24 | 7.67 | 7.41 | 7.77 |