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. 2021 Feb 17;22(4):1989. doi: 10.3390/ijms22041989

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cancer pathways and oncogene analysis concerning gender differences. (A) Dotplot of deregulated oncogenic pathways from KEGG analysis. The y-axis represents the name of the pathway, the x-axis represents the gene ratio, dot size represents the number of different genes and the color indicates the adjusted p-value. (B) Nodes are DE RNAs and are ranked according to fold change whereas edges indicate disease prognosis and are colored according to favorable (light blue) and unfavorable (orange) prognosis. (C) Pie graph displays the overall unfavorable or favorable prognosis. (D) Co-interaction network between lncRNAs on OBT2D vs. OBF and the oncogenes highlighted after OncoScore analysis. One main network was built, including a total of 3 lncRNAs: XIST, PAX8-AS1 and JPX. (E) The GEPIA2 database displays the specific annotated expression of each lncRNA in tumoral and normal tissues.