Table 1.
Prognosis score associated with each cancer. Unfavorable or favorable prognosis was assessed according to orange or blue edges, respectively. Upregulated or downregulated genes were described according to their log2FC. A bibliographic search was performed to assess previous correlations of each cancer type with obesity.
| Cancer | Unfavourable Prognosis | Favourable Prognosis | Literature Evidence for Obesity Correlation | ||
|---|---|---|---|---|---|
| Upregulated Unfavourable Prognosis | Downregulated Favourable Prognosis | Downregulated Unfavourable Prognosis |
Upregulated Unfavourable Prognosis |
||
| Stomach Cancer | 2 | 0 | 0 | 1 | Negatively correlated [34,35] |
| Ovarian Cancer | 2 | 0 | 0 | 2 | Positively correlated [36] |
| Thyroid Cancer | 2 | 0 | 0 | 0 | Positively correlated [37,38] |
| Colorectal Cancer | 2 | 1 | 0 | 4 | Positively correlated [39,40] |
| Breast Cancer | 2 | 4 | 0 | 8 | Positively correlated [7,41] |
| Cervical Cancer | 2 | 1 | 1 | 9 | Positively correlated [8,42] |
| Glioma | 3 | 1 | 0 | 0 | Negatively correlated [43] |
| Pancreatic Cancer | 10 | 2 | 1 | 0 | Positively correlated [44,45] |
| Melanoma | 0 | 0 | 0 | 2 | Positive correlation amongst men [46] |
| Head and Neck Cancer | 1 | 3 | 0 | 9 | Positively correlated [47] |
| Lung Cancer | 9 | 2 | 0 | 0 | Negatively correlated [48] |
| Renal Cancer | 44 | 8 | 4 | 7 | Positively correlated [49] |
| Liver Cancer | 15 | 6 | 2 | 1 | Positively correlated [50] |
| Urothelial Cancer | 5 | 2 | 1 | 3 | Positively correlated [51] |
| Endometrial Cancer | 7 | 1 | 1 | 14 | Positively correlated [52] |