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. 2021 Feb 19;26(4):1108. doi: 10.3390/molecules26041108

Table 1.

Baseline characteristics of patients.

Variable Overall (n = 90) STEMI (n = 46) NSTEMI (n = 44) p-Value
Age, years 67.2 ± 9.1 66.2 ± 8.8 68.2 ± 9.4 0.308 1
Male sex 71 (78.9%) 35 (76.1%) 36 (81.8%) 0.505 1
Body mass index, kg/m2 27.08 ± 2.54 27.45 ± 2.71 26.70 ± 2.31 0.158 3
Waist-to-hip ratio 1.04 ± 0.68 1.04 ± 0.68 1.04 ± 0.69 0.630 3
Systolic blood pressure, mmHg 134.7 ± 21.0 134.3 ± 21.3 135.1 ± 20.9 0.845 3
Diastolic blood pressure, mmHg 79.7 ± 12.6 81.2 ± 12.3 78.1 ± 12.9 0.252 3
Heart rate at admission, bpm 75.0 ± 16.9 76.7 ± 18.6 73.3 ± 14.9 0.353 3
Diabetes mellitus 13 (14.4%) 4 (8.7%) 9 (20.5%) 0.140 2
Arterial hypertension 51 (56.7%) 27 (58.7%) 24 (54.5%) 0.832 1
Smoking 43 (47.8%) 24 (52.2%) 19 (43.2%) 0.393 1
Dyslipidemia 14 (15.6%) 6 (13.0%) 8 (18.2%) 0.501 1
Atrial fibrillation 12 (13.3%) 8 (17.4%) 4 (9.1%) 0.355 2
Family history of cardiovascular disease 17 (18.9%) 10 (21.7%) 7 (15.9%) 0.480 1
History of PCI or CABG 16 (17.8%) 4 (8.7%) 12 (27.3%) 0.028 2
History of CV-related hospitalizations 24 (26.7%) 5 (10.9%) 19 (43.2%) 0.001 2
GRACE score, points 121.4 ± 22.0 121.1 ± 23.1 121.7 ± 23.1 0.906 3
Left ventricular ejection fraction, % 50.7 ± 10.3 51.2 ± 9.7 50.1 ± 11.1 0.652 3
Mean Killip class * 1.0 (1.0-1.0) 1.0 (1.0-1.0) 1.1 (1.0-1.0) 0.136 4
ST segment deviation in first contact ECG 82 (91.1%) 46 (100%) 36 (81.8%) 0.002 1
PCI performed while in-hospital 74 (82.2%) 44 (95.7%) 30 (68.2%) 0.001 1
Multi-vessel disease 10 (13.3%) 2 (4.4%) 8 (26.7%) 0.012 2
Beta-blocker use 29 (32.2%) 12 (26.1%) 17 (38.6%) 0.203 1
ACE inhibitor or ARB use 41 (45.6%) 21 (45.7%) 20 (45.5%) 0.985 1
Calcium channel blocker use 14 (15.6%) 8 (17.4%) 6 (13.6%) 0.623 1
Statin use 18 (20.0%) 6 (13.0%) 12 (27.3%) 0.092 1
Diuretic use 20 (22.2%) 8 (17.4%) 12 (27.3%) 0.260 1
Acetylsalicylic acid use 23 (25.6%) 7 (15.2%) 16 (36.4%) 0.021 1
P2Y12 inhibitor use 4 (4.4%) 1 (2.2%) 3 (6.8%) 0.355 2
Anticoagulant use 7 (7.8%) 4 (8.7%) 3 (6.8%) 1.000 2
Prothrombin time—INR 1.09 ± 0.39 1.07 ± 0.25 1.11 ± 0.50 0.608 3
Activated partial thromboplastin time, s 24.13 ± 4.02 23.96 ± 4.21 24.32 ± 3.85 0.672 3
C-reactive protein, mg/L 6.4 ± 5.0 6.6 ± 5.2 6.2 ± 4.9 0.664 3
High-sensitivity cardiac troponin I at admission, ng/L 331.0 ± 293.8 335.2 ± 306.1 326.9 ± 284.8 0.894 3
Potassium, mmol/L 4.04 ± 0.40 3.98 ± 0.39 4.10 ± 0.41 0.176 3
Urea, mmol/L 7.6 ± 3.2 7.0 ± 2.2 8.2 ± 4.0 0.094 3
Creatinine, μmol/L 0.428 88.0 ± 21.6 102.9 ± 44.3 0.045 3

Data are presented as mean ± standard deviation or n (%); * Data presented as median (interquartile range); 1 Chi-squared test; 2 Fisher’s exact test; 3 t-test for independent samples; 4 Mann–Whitney U test; WHO: World Health Organization; COPD: chronic obstructive pulmonary disease; PCI: percutaneous coronary intervention; CABG: coronary artery bypass grafting, CV: cardiovascular; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker; INR: international normalized ratio.