Table 3.
The baseline levels of miR-146, cfDNA, and total exosome protein content between young and elderly groups.
| Young (N = 12) | Elderly (N = 38) | p-Value | |
|---|---|---|---|
| Mean ± SEM | Mean ± SEM | ||
| miR-146a-5p (log10-scale) | 3.948 ± 0.482 | 4.3151 ± 0.214 | 0.618 |
| cfDNA (ng/mL) | 2277.079 ± 63.658 | 2443.279 ± 56.015 | 0.114 |
| Total exosome protein (µg/µL) | 5.022 ± 0.382 | 6.000 ± 0.328 | 0.140 |
| CD9 (O.D.) | 0.904 ± 0.179 | 1.049 ± 0.088 | 0.262 |
| CD14 (O.D.) | 1.850 ± 0.597 | 1.582 ± 0.164 | 0.486 |
| CD63 (O.D.) | 1.690 ± 0.218 | 1.499 ± 0.341 | 0.014 * |
| CD81 (O.D.) | 1.311 ± 0.295 | 1.101 ± 0.089 | 0.856 |
| Flot-1 (O.D.) | 1.879 ± 0.399 | 1.633 ± 0.365 | 0.125 |
| VDAC1 (O.D.) | 0.958 ± 0.152 | 1.530 ± 0.184 | 0.078 |
CD = cluster of differentiation; cfDNA = cell-free DNA; O.D. = optical density; VDAC1 = voltage-dependent anion channel 1; * p < 0.05.