a7nAChR	alpha-7 nicotinic acetylcholine receptor
ABCA1	ATP binding cassette A1
ABCB1	ATP-binding cassette sub-family B member 1
ACE	Angiotensin-converting enzyme
AD	Alzheimer’s disease
AJ	Adherent-junction
ApoE	Apolipoprotein E
APP	Amyloid precursor protein
AQP4	Aquaporin-4 water channels
ARB	Angiotensin receptor blocker
AT1	Angiotensin II type 1 receptor
Aβ	Amyloid β-peptide
BACE1	Beta-site APP cleaving enzyme 1
BBB	Blood-brain barrier
BDNF	Brain-derived neurotrophic factor
BEC	Brain endothelial cell
b-FGF	Basic fibroblast growth factor
C.p.	Clinical phase
Cx	Complement factors
CAA	Cerebral amyloid angiopathy
CBF	Cerebral blood flow
CCB	Calcium channel blocker
CNS	Central nervous system
COX-2	Cyclooxygenase-2
CR	Complement receptor
CSF	Cerebrospinal fluid
DDS	Drug delivery systems
eNOS	Endothelial nitric oxide synthase
fAβ	Fibrillar Aβ
Fc γ R	Fc γ receptor
Fyn	Proto-oncogene tyrosine-protein kinase Fyn
GDNF	Glial cell-derived neurotrophic factor
GLP-1	Glucagon-like peptide 1
GLUT	Glucose transporter
GSK3β	Glycogen synthase kinase 3β
HCHWA-D	Hereditary cerebral hemorrhage with amyloidosis-Dutch type
HImAb	Human insulin mAb
HMG-CoA	3-Hydroxy-3-methylglutaryl-CoA
HSA	Human serum albumin
IEL	Internal elastic lamina
IGF-1	Insulin-like growth factor 1
IgG	Immunoglobulin G
IL-1α	Interleukin-1 alpha
IL-1 β	Interleukin-1 beta
IL-1R1	Interleukin 1 receptor type 1
iNos	inducible nitric oxide synthase
IR	Insulin receptor
ISF	Interstitial fluid
LAMs	Leukocyte adhesion molecules
LRP1	Low-density lipoprotein receptor-related protein 1
mAb	Monoclonal antibody
mAβ	Monomeric Aβ
MEOX2	Mesenchyme homeobox gene 2
MMP	Matrix metalloproteinase
MTJ	Molecular Trojan horse
NF-kB	Nuclear factor-κB
NFT	Neurofibrillary tangle
NGF	Nerve growth factor
NMDAR	N-Methyl-d-aspartate receptors
NP	Neuritic plaque
NSAIDs	Non-steroidal anti-inflammatory drugs
NVU	Neurovascular unit
oAβ	Oligomeric Aβ
p47PHOX	Neutrophil cytosol factor 1
Pcp	Preclinical phase
PDGF-B	Platelet-derived growth factor subunit B
PDGFRβ	Platelet-derived growth factor receptor-β
PGE2	Prostaglandin-E2
P-gp	P-glycoprotein
PHF	Paired helical filament
PI3K	Phosphatidylinositol 3-kinase
PVMs	Perivascular macrophages
RAGE	Receptor for advanced glycation endproducts
RMT	Receptor-mediated transcytosis
ROS	Reactive oxygen species
sAPPα	Secreted ectodomain APP alpha
SAS	Subarachnoid space
SEC-R	Serpin-enzyme complex receptor
sLRP	Soluble low-density lipoprotein receptor-related protein
SMC	Smooth muscle cell
SRA	Class A scavenger receptor
SRB2	Scavenger receptor class B member 2
SREBP2	Sterol response element-binding protein 2
SRF	Serum response factor
TfR	Human transferrin receptor
TGF-β	Transforming growth factor-beta
TJ	Tight-junction
TLR	Toll-like receptor
TNF-α	Tumoral necrosis factor-α
TNFR	Tumoral necrosis factor receptor
TREM2	Triggering receptor expressed on myeloid cells 2
VEGF	Vascular endothelial growth factor
ZO-1	Zonula occludens-1
γ-PPAR	Peroxisome proliferator-activated receptor-γ