Table 3.
Pregnancy outcomes according to the type of fetal cardiac intervention.
| fBAV | fBPV | IAS | BAS | Total | p-Value | |
|---|---|---|---|---|---|---|
| Number of procedures/number of fetuses | 94/88 | 15/13 | 14/14 | 5/5 | 128/113 | NA |
| Gestational age at FCI (weeks) | 25 (20–32) | 24 (22–30) | 27 (22–33) | 24 (22–29) | 25 (20–33) | 0.407 |
| Procedure-related death of the fetus/neonate † | 7 | 1 | 2 | 1 | 10 | 0.655 |
| Procedure non-related death of the fetus | 3 | 0 | 0 | 0 | 3 | 0.776 |
| Live birth | 78 | 12 | 12 | 4 | 100 | 0.889 |
| Gestational age at birth (weeks) | 39 (29–41) § | 38 (33–40) | 37 (29–41) | 33.5 (29–39) § | 39 (29–41) | 0.041 |
| Mode of delivery VD/CS | 42/36 54%/46% |
6/6 50%/50% |
7/5 58%/42% |
3/1 75%/25% |
54/46 54%/46% |
0.837 |
| Time interval between intervention and birth (days) | 92 (17–162) | 100 (46–117) | 75 (11–109) | 57.5 (17–114) | 92 (11–162) | 0.025 |
| Birth weight (g) | 3330 (950–4950) # |
3130 (2100–3920) ^ |
3130 (1770–4090) |
2640 (1800–2860) #,^ |
3320 (950–4950) |
0.046 |
Data are given as median (range), number or %. p-value calculated with the Kruskal-Wallis test and multiple comparisons post-hoc test. CS: cesarean section; VD: vaginal delivery; NA: not applicable; † procedure-related death—fetal/neonatal death within 72 h following the procedure; § p = 0.030 (fBAV vs. BAS); # p = 0.001 (fBAV vs. BAS); ^ p = 0.048 (fBPV vs. BAS). Column “Total” is not the sum of previous columns, because in 14 patients more than one procedure was performed (the same FCI twice in eight cases, two different FCI in five cases, and three different FCI in one case).