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. 2021 Feb 17;22(4):1996. doi: 10.3390/ijms22041996
ACAN Aggrecan
ACI Autologous chondrocyte implantation
ACL Anterior cruciate ligament
ACLT Anterior cruciate ligament transection
ADAMTS A disintegrin and metalloproteinase with thrombospondin motifs
AI Artificial intelligence
ARGS Alanine–Arginine–Glycine–Serine
BMI Body mass index
C1,2C Type I/II collagen degradation
C2C Type II collagen cleavage product
C2M MMP-mediated type II collagen
CCL2 CC-chemokine ligand 2, also known as MCP-1
CH Chondrocyte
CHI3L1 Chitinase 3-like 1
CLU Clusterin
COLI Collagen I
COLII Collagen II
COMP Cartilage oligomeric matrix protein
CPII Procollagen II c-propeptide
CRP C-reactive protein
CS Chondroitin sulphate
CTX-I C-terminal crosslinked telopeptide type I collagen
CTX-II C-terminal crosslinked telopeptide type II collagen
CXCL Chemokine ligand
DAMPs Damage-associated molecular patterns
ECM Extracellular matrix
FB Factor B
FRI Fluorescence reflectance imaging
gp 130 Glycol–protein 130
HMGB1 High mo­bility group box 1
IFN-γ Interferon gamma
IL Interleukin
IL-1ra IL-1 receptor antagonist
IL-6R IL-6 receptor
iNOS Inducible NO synthase
KOOS4 Knee Injury and Osteoarthritis Outcome Score 4
LIF Leukemia inhibitor factor
LPS Lipopolysaccharide
MASP MBL-associated serine proteases
MBL Mannose binding lectin
MCL Medial collateral ligament
MSC Mesenchymal stem cells
MCP-1 Monocyte chemoattractant protein-1, also known as CCL2
MIP-1β Macrophage inflammatory protein-1 beta, also known as CCL4
MIP-3α Macrophage inflammatory protein-3 alpha, also known as CCL20
MMPs Matrix metalloproteinases
MMX Partial medial meniscectomy
MNC Mononuclear cells
MRI Magnetic resonance imaging
NLRP3 Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing-3
NO Nitric oxide
NTX-1 N-terminal telopeptides of type I collagen
OA Osteoarthritis
OCL Osteocalcin
OPN Osteopontin
PG Proteoglycan
PLGA Poly (lactic-co-glycolic acid)
PPA Pyrophosphate arthritis, also known as pseudogout
PRP Platelet rich plasma
PRR Pattern-recognition receptors
PTOA Post-traumatic osteoarthritis
RA Rheumatoid arthritis
SASP Senescence-associated secretory phenotype
SCSO Superficial zone chondrocytes
SF Synovial fluid
sGAG Sulfated glycosaminoglycan
SPARC Secreted protein acidic and rich in cysteine, also known as osteonectin
sTCC Soluble terminal complement complex
SnCs Senescent cells
TIMP Tissue inhibitor of metalloproteinases
TLRs Toll-like receptors
TNF-α Tumor necrosis factor alpha
TSG-6 Product of tumor necrosis factor alpha-stimulated gene 6
Th17 T helper 17
VEGF Vascular endothelial growth factor