Table 1.
Baseline characteristics, clinical findings, and pregnancy outcomes of the study population.
| Variables | Total (n = 115) |
Delivery ≥32 Weeks (n = 106) |
Delivery <32 Weeks (n = 9) |
p-Value |
|---|---|---|---|---|
| Maternal age, years | 34 (25–42) | 34 (25–42) | 35 (28–39) | 0.415 |
| Prepregnancy BMI, kg/m2 | 22.9 (19.0–36.2) | 22.9 (19.0–36.2) | 22.8 (20.4–27.3) | 0.577 |
| Current smoking | 1 (0.9%) | 1 (0.9%) | 0 (0.0%) | 1.000 |
| Multiparity | 57 (49.6%) | 54 (50.9%) | 3 (33.3%) | 0.655 |
| Prior miscarriage | 39 (33.9%) | 35 (33.0%) | 4 (44.4%) | 0.803 |
| Prior cesarean section | 20 (17.4%) | 19 (17.9%) | 1 (11.1%) | 0.999 |
| Prior preterm birth | 8 (7.0%) | 8 (7.5%) | 0 (0.0%) | 0.999 |
| IVF-ET | 17 (14.8%) | 14 (13.2%) | 3 (33.3%) | 0.227 |
| Prior conization | 10 (8.7%) | 9 (8.5%) | 1 (11.1%) | 0.844 |
| Pregestational diabetes mellitus | 2 (1.7%) | 1 (0.9%) | 1 (11.1%) | 0.192 |
| GDM | 11 (9.9%) | 10 (9.7%) | 1 (12.5%) | 0.852 |
| Preeclampsia | 2 (1.8%) | 1 (1.0%) | 1 (12.5%) | 0.182 |
| Chronic hypertension | 3 (2.6%) | 2 (1.9%) | 1 (11.1%) | 0.299 |
| Thyroid disease | 6 (5.2%) | 4 (3.8%) | 2 (22.2%) | 0.098 |
| GA at diagnosis | 22 w 6 d (16 w 1 d–28 w 6 d) |
22 w 5 d (16 w 1 d–28 w 6 d) |
23 w 5 d (17 w 0 d–26 w 3 d) |
0.599 |
| Cervical length, mm | 22.0 (10.0–25.0) | 22.0 (10.0–25.0) | 20.5 (13.0–24.0) | 0.103 |
| Funneling | 8 (7.0%) | 6 (5.7%) | 2 (22.2%) | 0.176 |
| Positive fibronectin | 27 (35.5%) | 22 (32.4%) | 5 (62.5%) | 0.256 |
| Progesterone type | ||||
| Vaginal suppository | 110 (95.7%) | 101 (95.3%) | 9 (100.0%) | 0.999 |
| IM injection | 5 (4.3%) | 5 (4.7%) | 0 (0.0%) | |
| GA at delivery | 38 w 2 d (18 w 5 d–41 w 0 d) |
38 w 3 d (33 w 1 d–41 w 0 d) |
27 w 0 d (18 w 5 d–31 w 6 d) |
<0.001 |
| Cesarean delivery | 62 (53.9%) | 55 (51.9%) | 7 (77.8%) | 0.337 |
| Birth weight, g | 3040 (830–4030) | 3110 (1760–4030) | 1075 (830–1830) | <0.001 |
| Apgar score <7 at 5 min | 3 (2.9%) | 2 (2.1%) | 1 (12.5%) | 0.296 |
| NICU admission | 21 (20.4%) | 13 (13.7%) | 8 (100.0%) | <0.001 |
Data are presented as the median (range) or number (%). BMI, body mass index; IVF-ET, in vitro fertilization-embryo transfer; GDM, gestational diabetes; GA, gestational age; IM, intramuscular; NICU, neonatal intensive care unit; w, weeks; d, days.